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Ipamorelin - 5 mg
Growth Hormone Peptides

Ipamorelin

Selective GHRP — stimulates natural growth-hormone release without cortisol or prolactin spikes.

$45.00
99.96% Purity Verified

Third-Party Tested by Verum Analytics

Batch: BIL-IPA-02-2602Feb 4, 2026
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Albert - Chief Researcher

Albert's Verdict

Ipamorelin is the cleanest GHS-R1a agonist in the catalog — highly selective for pituitary release with minimal cortisol or prolactin signal. That selectivity is exactly what you want when isolating ghrelin-receptor mechanisms.

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✓ In stock - Ships same day

Arrives as lyophilized (powder) form

Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.

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Product Description

Ipamorelin is a selective growth-hormone releasing peptide (GHRP) that stimulates natural pulsatile GH release from the pituitary gland. Its selectivity is what sets it apart — unlike older GHRPs, Ipamorelin does not meaningfully elevate cortisol, prolactin, or hunger, giving it the cleanest side-effect profile of any GH secretagogue.

Extensively researched for body composition, recovery, sleep quality, bone growth, and anti-aging applications. Most commonly paired with a GHRH such as CJC-1295 (No DAC) for a stronger, more synergistic GH pulse. For research use only. Not for human or veterinary consumption.

Technical Specifications

Molecular Formula
C38H49N9O5
Molecular Weight
711.85 g/mol
Sequence
Aib-His-D-2-Nal-D-Phe-Lys-NH2

Customer Reviews

Verified research purchases

5.0(8 reviews)
Matt S.Verified
1 week ago

My go-to source now

After trying a few different suppliers, I've settled on BioInfinity. The quality and service are consistently excellent. Highly recommend.

45 people found this helpful
Chris N.Verified
2 weeks ago

Verifiable quality

The ability to verify the COA on the testing lab's website is huge. This transparency sets BioInfinity apart from other suppliers.

52 people found this helpful
Nicole T.Verified
1 month ago

Reliable and trustworthy

I needed a reliable source with good documentation. BioInfinity delivered on all fronts. Will definitely order again.

38 people found this helpful
Susan M.Verified
3 weeks ago

Great customer service

Had questions about reconstitution and storage. The support team responded quickly with helpful answers. Great experience.

27 people found this helpful
Tony K.Verified
6 weeks ago

Bulk discounts are great

The quantity discounts make this more affordable than other options. Quality is top notch and shipping is fast. Win-win.

41 people found this helpful
Eric W.Verified
2 months ago

Quality you can trust

The COAs and third-party testing documentation give me confidence. This is what professional suppliers should look like.

58 people found this helpful
Diana L.Verified
4 weeks ago

Best value around

When you factor in quality, documentation, and service, BioInfinity offers the best value. I've tried others - this is my standard now.

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1 week ago

Fast shipping

Same-day shipping for orders before 2PM is clutch. Package arrived exactly when promised and in perfect condition.

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Frequently Researched Together

Commonly studied alongside in laboratory settings

Bundle total (3 items):$107.00

Research FAQ — Ipamorelin

Frequently asked questions about this compound for laboratory researchers.

What is Ipamorelin?+
Ipamorelin is a selective pentapeptide GHS-R (ghrelin-receptor) agonist. The 1998 publication describing its discovery characterized it as a selective growth hormone secretagogue in research models, with reduced reported effects on cortisol and prolaktin.
How is Ipamorelin different from GHRP-2 or GHRP-6 in research literature?+
Published comparative literature highlights Ipamorelin's selectivity for GHS-R and its reduced effect on other pituitary hormones relative to GHRP-2 and GHRP-6 in animal research models.
Is Ipamorelin commonly paired with CJC-1295 No DAC in research protocols?+
Yes — research literature describes combined administration as a way to investigate complementary GH-release pathways (GHRH-receptor + GHS-R). BioInfinity offers a pre-blended CJC-1295 + Ipamorelin vial for research convenience.
How should Ipamorelin be stored?+
Lyophilized at −20 °C protected from light; reconstituted held at 2–8 °C and typically used within 30 days. Refer to the product COA.

Published research references

Peer-reviewed literature relevant to Ipamorelin research. Linked PubMed IDs open the original source.

  1. [1]Ipamorelin, the first selective growth hormone secretagogue — Eur J Endocrinol (1998) · PMID 9849822
  2. [2]Selective GH secretagogues: Ipamorelin pharmacology — Growth Horm IGF Res (2008) · PMID 18430761
  3. [3]Pulsatile GH release with ghrelin-mimetic peptides — J Endocrinol (2001) · PMID 11457741
BL
Reviewed by the BioInfinity Research Team
Content reviewed by our research and quality team — biochemistry-degreed reviewers working alongside our analytical lab partner (Janoshik Analytical). Every product page is cross-checked against the cited peer-reviewed literature and the current batch's third-party COA.
For laboratory research use only. Not for human or veterinary use. Content is informational and does not constitute medical advice.

Verified reviews — Ipamorelin

1 verified buyer

5.0 / 5
Joshua E.Verified buyer
Jun 20, 2026
Pure!

Works as intended

Reviews are submitted by verified buyers via per-order tokenized links. Reviews are evaluated for product-focused content; any review containing therapeutic claims (cured, treats, healed, etc.) may be edited or hidden to maintain compliance with FDA and platform guidelines.

Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.

Research summary

Ipamorelin — clinical & mechanistic profile

Ipamorelin is the first GHRP with GHRH-like selectivity, binding GHSR-1a (ghrelin receptor) to stimulate pulsatile GH release with EC50 = 1.3 nmol/L and Emax = 85% comparable to GHRP-6, but without ACTH/cortisol elevation even at >200-fold above GH ED50. Lower plasma clearance (5-fold slower than GHRP-6) with ~50% nasal bioavailability.

Research status

clinical investigational

Sequence

Aib-His-D-2-Nal-D-Phe-Lys-NH2

Molecular weight

711.85 g/mol

Molecular formula

C38H49N9O5

Studied applications

  • Exceptional selectivity: no significant ACTH/cortisol elevation at >200-fold GH ED50, mirroring GHRH selectivity
  • GHRP-6 equivalent potency: EC50 = 1.3 ± 0.4 nmol/L, Emax = 85 ± 5% in rat pituitary; ED50 = 80 nmol/kg in vivo
  • Pulsatile GH release: dose-dependent peaks at 15-60 min, baseline by 180 min; synergistic with GHRH
  • Superior pharmacokinetics: 5-fold lower plasma clearance than GHRP-6, ~50% nasal bioavailability
  • GI-independent action: gastrectomy reduces GHRP-6 GH release 60-70%, suggesting gastric ghrelin component

Mechanisms of action

  • GHSR-1a agonism: selectively binds ghrelin receptor, confirmed via GHRP antagonist pharmacology (not GHRH pathway)
  • Pituitary somatotroph activation: directly stimulates GH-producing cells via Gq-protein/calcium signaling
  • Hypothalamic modulation: may upregulate GHRH mRNA in arcuate nucleus, downregulate somatostatin in periventricular nucleus
  • Calcium influx: triggers intracellular Ca2+ signaling from IP3-mediated stores for GH vesicle release
  • Pathway selectivity: minimal cross-talk to ACTH-releasing or prolactin-releasing pathways
  • Synergistic with GHRH: amplifies GH pulse through complementary cAMP (GHRH) and Ca2+ (ipamorelin) pathways
Research constraints & safety notes
  • Not approved for human therapeutic use—research compound only
  • Clinical development for postoperative ileus discontinued
  • Short half-life (~2 hours) requires multiple daily administrations
  • GH elevation may affect glucose metabolism
  • Quality and purity of research compounds varies between sources

Peer-reviewed references

  1. Raun K, et al. — Ipamorelin selectivity and GH secretion (1998)PMID: 9849822View
  2. Ipamorelin vs. other GHRPs selectivity comparison (2001)PMID: 11452249View
  3. Pharmacokinetics and mechanism studiesPMID: 16352683View
  4. GHRPs hypothalamic GHRH/somatostatin modulationPMID: 8950613View
  5. Ipamorelin pharmacokinetics, nasal bioavailabilityPMID: 9879640View

For research use only. This summary is a research-scientific overview compiled from peer-reviewed sources. It is not medical advice and is not intended for human or veterinary consumption.