Research Peptide · US Supplier
Buy MOTS-c in the USA
MOTS-c (Mitochondrial Open-reading-frame of the Twelve S rRNA-c) supplied for laboratory research. ≥99% HPLC purity, batch-matched third-party COA, cold-chain packaging.
About This Compound
MOTS-c is a 16-amino-acid mitochondrially-encoded peptide first described by the Cohen laboratory at USC in 2015. It is one of a small handful of biologically-active peptides transcribed from within mitochondrial DNA rather than the nuclear genome, and has become a highly-cited tool compound in mitochondrial-signalling and cellular-bioenergetics research.
Sequence: MRWQEMGYIFYPRKLR (MW 2174 Da). The compound is investigated in the preclinical literature for its role in AMPK-pathway signalling, mitochondrial-nuclear communication, glucose-metabolism preclinical models, and skeletal-muscle metabolic-substrate handling.
BioInfinity's MOTS-c is synthesized by SPPS, purified by preparative HPLC to ≥99%, and identity-confirmed by ESI-MS. Endotoxin below 0.5 EU/mg by LAL. Batch-matched Verum Analytics third-party COA with every order.
Presented as a lyophilized white powder in septum-sealed 5 mg or 10 mg vials for reconstitution with bacteriostatic water for laboratory use. Store refrigerated 2–8 °C, long-term −20 °C protected from light.
Quality Benchmarks
Every batch shipped from BioInfinity is verified against these specifications by an independent third-party lab before release.
- Purity
- ≥ 99% by reverse-phase HPLC
- Identity
- Confirmed by ESI-MS mass spectrometry
- Endotoxin
- < 0.5 EU/mg (LAL assay)
- Third-Party COA
- Verum Analytics (Switzerland) — batch-matched
- Origin
- Solid-phase peptide synthesis (SPPS), Fmoc chemistry
- Presentation
- Lyophilized white powder, septum-sealed vial
- Storage
- Refrigerate 2–8 °C; long-term −20 °C, protect from light
- Batch Traceability
- Every vial tied to a lot number & verification code
Research Applications in the Literature
Non-exhaustive list of subjects investigated in the published preclinical / in-vitro literature. Provided for research-context reference only — not a claim of efficacy.
- AMPK-signalling pathway in-vitro studies
- Mitochondrial-nuclear retrograde communication research
- Skeletal-muscle metabolic-substrate handling models
- Glucose-uptake preclinical assays
- Insulin-sensitivity in-vitro literature
- Cellular bioenergetics / Seahorse XF assay tool compound
- Aging-model preclinical research
- Mitochondrial-derived-peptide biology reference standard
Frequently Asked Questions
Where can I buy MOTS-c in the USA?▾
BioInfinity is a US-based research peptide supplier shipping MOTS-c same-day from our Manhattan facility. Every vial ships with a batch-matched third-party Certificate of Analysis (COA) and includes cold-chain packaging when the transit route requires it.
What purity is your MOTS-c?▾
Our MOTS-c is ≥ 99% pure by reverse-phase HPLC, identity-confirmed by mass spectrometry, and endotoxin-tested via LAL assay. The exact assay values for the batch you receive are published on your product page and are also included as a printed COA in the shipment.
Do you provide a Certificate of Analysis (COA) with MOTS-c?▾
Yes. Every shipment includes a batch-matched COA from an independent third-party laboratory (Verum Analytics, Switzerland). You can also verify the batch online in our public COA library using the verification code printed on the vial label — no login required.
How is MOTS-c shipped?▾
USPS Priority (2-3 business days) or UPS Ground (3-5 days). Cold-chain packaging with gel packs sized to the transit route. Discreet plain unbranded outer boxes — the label carries only the address and standard postal markings.
What payment methods can I use for MOTS-c?▾
Credit / debit card (Visa, Mastercard, Amex, Discover), Zelle, Venmo, Cash App, USDC stablecoin, and wire transfer for institutional orders. Zelle typically clears fastest and is the most common payment method our repeat customers use.
Is MOTS-c FDA-approved or intended for human use?▾
No. MOTS-c is not FDA-approved for any therapeutic indication. BioInfinity supplies MOTS-c strictly for in-vitro laboratory research. It is not intended for human, veterinary, or in-vivo use of any kind.
How should I store MOTS-c once it arrives?▾
The lyophilized (freeze-dried) powder is stable at 2–8 °C refrigeration for normal-use timeframes. For extended storage until the expiry date, store at −20 °C protected from light. Once reconstituted for bench work, refrigerate at 2–8 °C and use within 3–4 weeks per general peptide-handling literature.
Can I get a bulk / institutional discount on MOTS-c?▾
Yes. Professional accounts qualify for tiered volume discounts. Create a Professional account at /account, or e-mail [email protected] with your institution and PO details.
What is your return policy on MOTS-c?▾
Unopened, cold-chain-intact vials can be returned within 14 days of delivery for a refund minus return shipping. Opened vials are non-returnable due to the nature of the product. If a shipment arrives damaged or thawed, contact us within 48 hours for a free replacement.
How fast do orders for MOTS-c ship?▾
Orders placed by 3:00 PM ET Monday–Friday ship same-day from Manhattan. Weekend orders ship the following Monday. You'll receive a tracking number by email the moment the label is scanned by USPS or UPS.
Do you ship MOTS-c internationally?▾
We ship domestically within the 50 United States plus Puerto Rico and the US Virgin Islands. International shipments are evaluated case-by-case and require additional documentation — please contact [email protected] for a quote.
Where can I read your MOTS-c COA?▾
Every batch's COA is browsable from our public /coa-library page. You can also click the "View COA" button on the MOTS-c product page (/product/mots-c) or on the vial label itself, which carries a QR code that resolves to the batch's verification page.
What sizes does MOTS-c come in?▾
5 mg and 10 mg septum-sealed lyophilized vials. Institutional bulk sizes on request.
Is MOTS-c encoded by nuclear DNA?▾
No — MOTS-c is one of the small number of biologically-active peptides transcribed from within mitochondrial DNA (specifically, the 12S rRNA region), which is what makes it a landmark tool compound in mitochondrial-signalling research.
Related Research Peptides
Frequently sourced together by research groups.
Ready to Order?
Same-day shipping from our Manhattan facility. Third-party Certificate of Analysis included with every shipment.
All products sold by BioInfinity are supplied strictly for in-vitro laboratory research use only. They are not FDA-approved for any therapeutic indication and are not intended for human or veterinary use.