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BLENDCJC-1295 + Ipamorelin - 10 mg Blend
Growth Hormone Peptides

CJC-1295 + Ipamorelin

CJC-1295 (No DAC) + Ipamorelin — the gold-standard GHRH + GHRP stack for natural growth-hormone release.

$95.00
99.57% Purity Verified

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Batch: BIL-CP10-01-2602Feb 4, 2026
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Albert - Chief Researcher

Albert's Verdict

Stacking CJC-1295 without DAC with Ipamorelin gives you GHRH and GHS-R1a stimulation on two distinct pathways simultaneously. The pulse amplitude data on pituitary secretion from this combination is consistently stronger than either compound in isolation.

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Arrives as lyophilized (powder) form

Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.

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Product Description

CJC-1295 + Ipamorelin is the most popular growth-hormone research stack, pairing a GHRH analog (Modified GRF 1-29) with a highly selective ghrelin-receptor agonist (Ipamorelin). The two peptides act on separate pituitary pathways, producing a stronger and cleaner pulsatile release of natural growth hormone than either peptide alone.

Extensively studied for body composition, recovery, sleep quality, and anti-aging applications. The Ipamorelin component is prized for its clean profile — no meaningful spikes in cortisol or prolactin — making this combo the preferred choice for researchers investigating natural GH optimization. For research use only. Not for human or veterinary consumption.

Technical Specifications

Molecular Formula
C152H252N44O42 + C38H49N9O5
Molecular Weight
3367.97 + 711.85 g/mol

Frequently Researched Together

Commonly studied alongside in laboratory settings

Bundle total (3 items):$157.00

Verified reviews — CJC-1295 + Ipamorelin

5 verified buyers

5.0 / 5
Cody R.Verified buyer
Jun 13, 2026
Fast shipping. Quality product.

Professionally packaged and arrived in just a few days. Will order again.

Kevin G.Verified buyer
Jun 11, 2026
Good product

fast shipping and product working as expected, I'm happy with the product.

Mandy K.Verified buyer
Jun 11, 2026
CJC 1295/IPA

This was one of our first peptides purchased and it has been excellent. Fast delivery and excellent product!!

Cruz U.Verified buyer
Jun 11, 2026
Trusted Partner

We were able to reconstitute and use it immediately. The level of purity is perfect and has made an impact.

Claudette A.Verified buyer
Jun 11, 2026
Fast shipping

Great quality!

Reviews are submitted by verified buyers via per-order tokenized links. Reviews are evaluated for product-focused content; any review containing therapeutic claims (cured, treats, healed, etc.) may be edited or hidden to maintain compliance with FDA and platform guidelines.

Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.

Research summary

CJC-1295 without DAC (Mod GRF 1-29) — clinical & mechanistic profile

Mod GRF 1-29 is a tetrasubstituted GHRH analog (Ala2, Gln8, Ala15, Leu27) with ~30-minute half-life (vs ~7 min native GHRH) due to DPP-IV resistance. Lacking DAC's albumin binding, it produces acute pulsatile GH release mimicking physiology, synergizing with GHRPs via complementary cAMP/Ca2+ pathways.

Research status

preclinical

Molecular weight

3367.95 g/mol

Molecular formula

C152H252N44O42

Studied applications

  • Preserved pulsatility: ~30 min half-life produces discrete GH spikes mimicking physiological patterns
  • DPP-IV resistance: Ala2 substitution blocks primary degradation enzyme, extending duration from ~7 to ~30 min
  • GHRP synergy: cAMP pathway (GHRH) + Ca2+/IP3 pathway (GHRPs) produce amplified GH pulses beyond additive effects
  • Flexible protocols: short duration allows timing with natural GH windows (sleep, exercise)
  • No albumin binding: lacks DAC moiety, enabling rapid clearance and pulsatile administration

Mechanisms of action

  • GHRHR full agonism: binds pituitary GHRH receptor, triggering Gs-protein coupling and adenylyl cyclase
  • cAMP/PKA pathway: adenylyl cyclase → cAMP → PKA activation → GH gene transcription and vesicle release
  • DPP-IV resistance: Ala2 substitution blocks dipeptidyl peptidase IV cleavage site
  • Synergistic signaling: complements GHRP Ca2+/IP3 pathway for amplified somatotroph activation
  • Dose-dependent peaks: produces sharp GH spikes 15-60 min post-injection, baseline by 180 min
Research constraints & safety notes
  • Not approved for human therapeutic use
  • Short half-life requires 2-3 daily injections for meaningful effects
  • No completed human clinical trials for this specific compound
  • Quality and purity of research compounds varies
  • Optimal dosing and timing protocols not established

Peer-reviewed references

  1. CJC-1295 pharmacokinetic studies (2006)PMID: 16352683View
  2. GHRH analogs and pituitary functionPMID: 2699646View
  3. Wikipedia — CJC-1295 structure and modifications
  4. Paragon Sports Medicine — Mod GRF 1-29 mechanism review

For research use only. This summary is a research-scientific overview compiled from peer-reviewed sources. It is not medical advice and is not intended for human or veterinary consumption.