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Third-Party Tested by Verum Analytics
Quad-peptide regenerative blend — GHK-Cu + TB-500 + BPC-157 + KPV. The most complete tissue-repair stack available.
Third-Party Tested by Verum Analytics
Albert's Verdict
Lab-verified purity exceeding 99%. Certificate of Analysis available for review.
View COA✓ In stock - Ships same day
Arrives as lyophilized (powder) form
Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.
Researchers also added
KPV is a synthetic tripeptide (C-terminal α-MSH fragment). KPV is the C-terminal tripeptide of α-MSH that exerts anti-inflammatory effects via PepT1 transport and NF-κB inhibition, independent of melanocortin receptors. Reduces disease activity in murine colitis by >50%, suppresses LPS-induced cytokines by 60% in macrophages, and shows direct antimicrobial activity against S. aureus and C. albicans while sparing mammalian cells. It has a molecular formula C16H30N4O4, mass 342.43 Da. Its published amino-acid sequence is Lys-Pro-Val. Common synonyms in the literature include α-MSH fragment, Alpha-MSH 11-13, and Lys-Pro-Val. This SKU is a co-formulated blend that also contains GHK-Cu in the same vial — for research groups that want to combine the two under a single reconstitution.
Investigation of KPV to date is primarily preclinical, with the majority of citations concentrated in animal models and in-vitro assays rather than randomized controlled human trials. Published work referencing KPV spans NF-κB inhibition studies: In vitro research in macrophages, intestinal epithelial cells, and other cell types demonstrates KPV suppresses NF-κB activation in response to LPS, IL-1β, or TNF-α stimulation. This reduces downstream transcription of inflammatory genes, Gut inflammation models: Studies in colonic inflammation models show KPV promotes mucosal healing, downregulates TNF-α expression, and protects against ulcerative damage when delivered to inflamed intestinal tissue, and IL-1 receptor antagonism research: KPV mimics the KPT loop of IL-1 receptor antagonist degradation products, binding IL-1RI to terminate IL-1β signaling. This represents a melanocortin receptor-independent anti-inflammatory mechanism. Proposed mechanisms in the literature include PepT1 intracellular uptake: transported via PepT1 (required for activity; blocking with Gly-Leu abolishes effects) and NF-κB pathway inhibition: inside cells, inhibits NF-κB activation via interactions with nuclear transport proteins (importins). None of this material describes therapeutic outcomes in humans, and BioInfinity does not sell, market, or provide dosing guidance for KPV outside laboratory research.
Lyophilized KPV arrives as a fluffy off-white solid inside a sealed sterile vial. Because it ships as a lyophilized peptide (342.43 Da), the powder is best stored between 2–8 °C prior to reconstitution and returned to −20 °C in aliquots for long-term storage post-reconstitution. Reconstitution is typically performed with bacteriostatic water (0.9 % benzyl alcohol preserved) rather than sterile water because the preservative extends solution stability once the vial has been punctured. Warming the reconstituted solution to room temperature before drawing helps redissolve any peptide that has settled against the vial wall. Avoid repeated freeze–thaw cycles: for peptides in this molecular-weight range (342.43 Da), freeze–thaw stress is one of the most common causes of loss-of-purity between batches.
Every batch of KPV ships with a batch-specific Certificate of Analysis produced by an ISO-accredited third-party analytical laboratory. Reversed-phase HPLC confirms the assay against the expected 342.43 Da mass (C16H30N4O4); mass spectrometry validates the exact monoisotopic mass; endotoxin (LAL) testing confirms bacterial-contamination limits appropriate for laboratory research; and residual-solvent panels confirm the manufacturing pipeline. The lot number on the outer label matches the COA on the public /coa-library page — every purity claim is independently verifiable before you open the vial.
For the full mechanistic profile, published references, and constraint notes on KPV, see the KPV research page. All references cited on that page are peer-reviewed primary literature.
Research use only. KLOW Blend is sold strictly for in-vitro and animal research. It is not a drug, food, supplement, or cosmetic and is not intended for human or veterinary consumption. No statements on this page describe or imply any therapeutic effect.
Verified research purchases
Been searching for a reliable supplier for months. The purity is legit - you can verify it yourself on the lab's website. Shipped fast and arrived cold. Will definitely reorder.
This is my go-to source now. Consistent quality every time, and the customer service actually responds when you have questions. The quantity discounts are a nice bonus too.
After trying 3 different suppliers, this one stands out. The COA is verifiable, shipping is fast, and the product quality speaks for itself. Highly recommend.
Ordered before 2PM and it shipped the same day. Package arrived in perfect condition with ice packs still frozen. That's how it should be done.
You get what you pay for. The third-party testing and COA verification gives me confidence. Already placed my second order.
Love that I can verify the COA directly on Verum's website. The full analytical report with HPLC chromatogram checked out. This level of transparency is rare.
Proper packaging, cold shipping, and everything documented. You can tell they take quality seriously. Already recommended to friends.
I've ordered multiple times and the quality is always the same. That consistency is why I keep coming back. No surprises, just quality product.
Commonly studied alongside in laboratory settings
Frequently asked questions about this compound for laboratory researchers.
Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.
