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Third-Party Tested by Verum Analytics
Selank
Anxiolytic and nootropic peptide — benzodiazepine-equivalent calm without sedation or dependency.
Third-Party Tested by Verum Analytics

Albert's Verdict
Selank's anxiolytic profile without sedation is what makes it stand out in the cognitive category. The BDNF upregulation data suggests it's doing more than modulating GABA — there's a genuine neuroprotective signal worth studying.
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Arrives as lyophilized (powder) form
Shipped freeze-dried for maximum stability and shelf life. See laboratory preparation guide for handling instructions.
Product Description
Selank is a synthetic heptapeptide analog of the naturally occurring immune peptide tuftsin, developed by the Russian Academy of Sciences. It has been extensively studied for its ability to reduce anxiety, sharpen cognition, and modulate the immune system — without the sedation, tolerance, or withdrawal seen with traditional benzodiazepines.
Clinical trials with 62+ patients showed anxiolytic effects comparable to medazepam with additional benefits: BDNF upregulation, cognitive enhancement, immune modulation (CD4+/CD8+ normalization), enhanced NK cell activity, and neuroprotective effects. A staple of anxiety and cognitive-performance research. For research use only. Not for human or veterinary consumption.
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The purity is exactly what they claim. I verified the COA on the lab's website and it checked out. Fast shipping too.
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Frequently Researched Together
Commonly studied alongside in laboratory settings
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Learn More About This Peptide
Research Use Only: This product is intended for laboratory research purposes only. Not for human consumption.
Selank — clinical & mechanistic profile
Selank is a synthetic heptapeptide analog of tuftsin with additional glyproline residues, developed in Russia and investigated for anxiolytic, nootropic, neuroprotective, and immunomodulatory effects through GABAergic and neurotransmitter system modulation.
Research status
mixed
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular weight
751.88 g/mol
Molecular formula
C33H57N11O9
Studied applications
- •Anxiolytic effects: demonstrates activity comparable to low-dose benzodiazepines without sedation or dependence
- •GABAergic modulation: allosterically affects GABA-A receptors, increasing GABA binding affinity
- •Nootropic research: studied for cognitive enhancement, memory, and attention effects
- •Immunomodulation: influences IL-6 expression, T helper cell balance, and enkephalin stabilization as tuftsin analog
- •BDNF elevation: rapidly increases brain-derived neurotrophic factor in hippocampus
Mechanisms of action
- •GABA-A receptor allosteric modulation: increases GABA binding affinity, mimicking benzodiazepine-like actions without side effects
- •Enkephalin system: inhibits enkephalin-degrading enzymes, increasing leu-enkephalin half-life
- •Serotonin/dopamine modulation: affects monoaminergic neurotransmission in mood and anxiety circuits
- •BDNF upregulation: rapidly elevates brain-derived neurotrophic factor for neuronal health
- •Hypocretin gene expression: normalizes sleep-wake balance through Hcrt gene modulation
- •Tuftsin receptor interaction: modulates immune function through tuftsin pathway activation
- •Approved only in Russia—not FDA approved or available by prescription in Western countries
- •Limited Western clinical data—most research from Russian institutions
- •Intranasal administration primarily studied—other routes less characterized
- •Long-term safety data limited even in approved jurisdiction
- •Independent replication of findings in Western laboratories is sparse
Peer-reviewed references
- Uchakina ON, et al. — Selank immunomodulatory mechanismsPMID: 19515342View
- Semenova TP, et al. — Selank GABA system interactions (2017)PMID: 28643444View
- Zozulia AA, et al. — Selank clinical anxiolytic studiesPMID: 18454096View
- Selank effects on neurotransmitter systemsPMID: 27403905View
- Selank positive allosteric modulation of GABA_A receptorsPMID: 30255741View
For research use only. This summary is a research-scientific overview compiled from peer-reviewed sources. It is not medical advice and is not intended for human or veterinary consumption.